Mesothelioma and Non Asbestos Exposure
Mesothelioma typically develops in the lining of the lungs (pleura) and abdomen (peritoneum). This rare cancer also can develop in the heart's lining (pericardium) or testes.
Asbestos is a major risk factor for mesothelioma. However, some patients diagnosed with mesothelioma may not have a history of asbestos exposure.
Exposure to Asbestos
Asbestos is a naturally occurring mineral that was once employed in industrial and construction products worldwide. sparks asbestos lawyer in asbestos-related industries handled the material every day and were at risk of exposure. Asbestos fibers can get stuck in the lungs which can lead to progressive lung disease. This is known as asbestosis. Over time, these fibers that are trapped in the lungs may cause mesothelioma. Asbestos fibers can be breathed in, ingested or even absorbed through the skin. The risk of developing mesothelioma or other asbestos-related diseases rises when exposed.
The majority of mesothelioma cases are the result of occupational exposure. Asbestos is used in many jobs, including electrical work and vehicle maintenance. These occupations are generally predominantly male-dominated and, as a result mesothelioma-related cases of males account for 75-80 percent of all cases reported. However, the phasing out of asbestos in the United States and other first-world countries has reduced exposure to asbestos on the job. This has resulted in an increase in cases as asbestos exposure outside of the workplace increasing in frequency.
Non-occupational mesothelioma can develop when asbestos is released from the workplace environment or found in the home or school environment. Exposure to asbestos from the outside can cause it, for example when a family member is exposed to the clothes worn by an asbestos worker. Those who experience this type of exposure may have symptoms like breathlessness or chest pain, which is often mistaken for lung or heart conditions.
Certain studies have found a link between non-occupational exposure and mesothelioma. However, the results aren't consistent. Many of these studies have been conducted on a limited sample size, and the between-study the degree of heterogeneity is high. Further research is needed to establish the connection between mesothelioma and exposure to non-occupational substances.
Those with non-occupational exposure should discuss their asbestos medical history with their doctor. If they are concerned, they should ask for a mesothelioma examination and referral to a specialist. Mesothelioma specialists can offer patients the best treatment and care options to improve their prognosis. They will look over medical records and perform imaging tests to determine if mesothelioma is present. They will also offer advice on how to file a mesothelioma suit to receive compensation from an asbestos trust fund.
Secondhand Exposure
Asbestos exposure is the most frequent mesothelioma-related cause. However, it is not the only cause. In fact, there is some evidence that people can get mesothelioma even though they never directly handled asbestos or worked in an industry that involved asbestos-related activities. This is referred to as secondary or non-occupational exposure.
Asbestos fibers are very small and can adhere to clothing, hair or skin as well as other surfaces. Workers may carry harmful fibers in their work clothes at home and then pass them on to family members. The asbestos fibers can cause mesothelioma when they are inhaled or ingestion.
This form of mesothelioma is more common in women, and usually occurs in the lung. However, it could also occur in the abdomen or chest wall. Shortness of breath is the most common indication. It can be caused by a variety of other symptoms, like fluid in the lungs or swelling in the scrotum.
Pleural mesothelioma refers to the name that is used to describe mesothelioma, which is found in the lungs. Peritoneal mesothelioma is the term used for mesothelioma that affects the stomach wall or the chest wall. This kind of mesothelioma may cause a number of symptoms like abdominal pain, difficulty in breathing, and constipation.
Numerous studies have revealed that even those who have no prior previous history of exposure to asbestos can still develop mesothelioma due to exposure to harmful fibers. These individuals usually lived with someone who was exposed to asbestos. They could have worn the clothing of an asbestos worker, or had other contact.
Veterans are at risk of developing mesothelioma due to the extensive use of asbestos in military bases, ships and vehicles. The Navy is particularly at risk because asbestos was used to insulate the hull the ship as well as to protect gun turrets. Asbestos was also often brought home by sailors who had returned from their work on ships that were infected with asbestos.
Environmental Exposure
A variety of substances have been linked to mesothelioma. The disease is still most often associated with asbestos exposure. Asbestos is a mineral that occurs naturally that was used for many years in manufacturing. It is a heat-resistant material and tough, which makes it ideal for insulation, brakes, flooring, shingles, and other products. When asbestos is broken up, it creates dust which can be inhaled or swallowed. The asbestos fibers can remain in the stomach and lungs for a long time, and trigger mesothelioma-related symptoms.
The most frequent symptoms of mesothelioma include chest pain, abdominal discomfort and difficulty breathing. Asbestos victims may suffer from these symptoms for 20 to 60 years or more following their initial exposure. The symptoms can be misinterpreted as other diseases, therefore it is important to see a doctor if you have these symptoms. Notifying your doctor of asbestos exposure is important. This can prevent a wrong diagnosis and ensure that you receive the proper treatment.
The most commonly affected mesothelioma patients from asbestos exposure are those who been directly exposed to asbestos but it is possible for loved relatives to be affected. This is referred to as secondary exposure. Family members can inhale or swallow asbestos fibers that are present in a worker's clothing, shoes or even tools. These particles could also be brought home by someone wearing or having their hair. This is the reason that mesothelioma sufferers and their families should wash their clothes in a clean manner after working with asbestos.
There is a substantial amount of research that shows a link between nonasbestos and mesothelioma. However there is no conclusive conclusions regarding the role played by other agents. There is evidence that suggests that the zeolites, erionite and chlorosotile are able to cause mesothelioma. Erionite is found in the soil and rocks in some areas of Turkey in which mesothelioma incidences are high in pleural mesot.
The research on the connection between mesothelioma exposure and asbestos exposure is ongoing. Funnel plots have revealed the possibility of publication bias, and there is a high degree of heterogeneity between studies. It is clear that asbestos exposure is the most significant mesothelioma-related risk factor.
Genetics
The mesothelioma-related rare disease occurs when malignant cells of the mesothelium grow uncontrollably and invade surrounding tissues. It is also able to spread throughout the body via the blood or lymphatic system, affecting other organs. Although asbestos is the principal mesothelioma trigger, it isn't the sole risk factor. Other genetic and environmental factors can trigger the condition.
Some cases of mesothelioma have been seen in people who were not exposed directly themselves to asbestos. They are known as non-occupational mesothelioma sufferers. These individuals were typically exposed indirectly by the handling of contaminated clothing or household items by anyone who was exposed to asbestos in their home. It is possible to be diagnosed with mesothelioma following inhaling asbestos fibers from the clothing of a family member. Research has shown that these types of mesothelioma cases are more likely to have longer latency periods and are more likely to be diagnosed in wives than in husbands.
Scientists are currently investigating the possibility that mesothelioma's genetic predisposition might play a role in the development of the disease. Recent studies have revealed that mutations in BAP1 gene could increase the risk of mesothelioma developing in people who are exposed to asbestos. This is significant because it could lead improved screening methods for those who are at risk of developing mesothelioma.
Researchers have identified a variety of genes that are linked to mesothelioma. Some of these genes are involved in suppressing the growth of tumors, and are often mutated or altered in mesothelioma patients. These genes include the large homolog 2 of tumor suppressor (LATS2) and NF2.
People with a family history of mesothelioma are at greater chance of contracting the mesothelioma. Certain genes, like BAP1, for instance, BAP1 that are passed down from parents. Asbestos was a common ingredient in the military for many years and veterans have the highest rates of mesothelioma in comparison to other occupational groups. The people who served on ships and in the Navy were at the highest risk of developing asbestos-related cancer due to exposure in the construction of ships, insulation and fireproofing materials.